Effects of LBP on expression of Bcl-2-associated death promoter (BAD), cytochrome C (cytC) and cleaved caspase-3, and intracellular calcium and mitochondrial permeability after 4 h OGD exposure. (A) LBP did not affect expression of Bad, cytC, or cleaved caspase-3 when these neuronal protein levels stabilized after 1 h OGD. However, in response to 4 h OGD, application of LBP significantly blocked the increase in expression of Bad, cytC and cleaved caspase-3 (B), antagonized the enhancement in intracellular calcium (Fluo-4) (C), and reduced mitochondrial permeability that was detected by Rhodamine 123 (Rohd 123, D; *P < 0.05; **P < 0.01; ##P < 0.01).