Effects of LBP on the expression of NR2B, PSD95, nNOS and production of ROS after exposed to 1 h or 4 h OGD. (A) Expression of NR2B, PSD95 and nNOS by neurons in response to different durations of OGD. (B) Administration of LBP blocked the increase in expression of NR2B and nNOS when neurons were exposed to OGD for 1 h. (C) LBP application antagonized the increase in nNOS expression, but did not further inhibit NR2B when NR2B level was reduced after 4 h OGD. (D) LBP application blocked the increase in ROS production 4 h OGD exposure (*P < 0.05; **P < 0.01; ##P < 0.01).