Histology of the mPFC is depicted in Figure 5(Fig. 5). Accordingly, there were no significant changes in the histological appearance of the control group compared to other groups, including curcumin, olive oil, grid with curcumin, and grid with olive oil. In addition, the SD animals showed a lower cell population. The remaining cells also seemed shrunk, pyknotic, and smaller in comparison to the control group. These histological changes seemed to have recovered in the SD+curcumin animals.