To investigate the biological processes abrogated by OGID pathogenic mutations, we performed functional enrichment analysis using the GO molecular function terms and KEGG pathway gene sets in g:Profiler.24 The chromatin binding (FDR q value = 1.58 × 10−6) and PI3K/AKT signaling pathway (FDR q value = 6.80 × 10−5) gene sets were significantly enriched.