Transplant outcomes
In the seven donor lungs that were transplanted, perfusion and ventilation parameters remained stable or improved during assessment. The data on changes in lung compliance, airway resistance, PVR, perfusate flow, and ventilation and perfusion pressures are shown in Fig. 1.
None of the recipients required extracorporeal life support. Two patients (29%) suffered from PGD (Grade 3) at 72 h post-transplant. However, both patients responded well to standard management. All seven recipients survived to hospital discharge. One recipient died of severe pneumonia at 11 months post-transplant due to an influenza infection unrelated to the EVLP procedure. The other six (86%) remain alive and well >2 years after transplant (Table 2).