Funding This work was supported by Symetis SA, Ecublens, Switzerland. Conflict of interest: Jochen Börgermann is a consultant and proctor for Medtronic and receives speaker honoraria and travel compensation from Medtronic, Symetis and Edwards Lifesciences. David M. Holzhey is an advisor for Edwards Lifesciences and Medtronic, and a proctor for Symetis. Steffen Hoffmann is a proctor for Symetis. Hendrik Treede is proctor and advisor for Symetis. Jörg Kempfert is a proctor for Symetis and receives travel compensation and speaker honoraria. The other authors declared no conflict of interest.