PMC:539297 / 3023-3351 JSONTXT

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    craft-ca-core-dev

    {"project":"craft-ca-core-dev","denotations":[{"id":"T564","span":{"begin":47,"end":55},"obj":"PR:000005591"},{"id":"T565","span":{"begin":92,"end":103},"obj":"SO:0000704"},{"id":"T566","span":{"begin":117,"end":122},"obj":"NCBITaxon:10088"},{"id":"T567","span":{"begin":130,"end":134},"obj":"PR:000005591"},{"id":"T568","span":{"begin":150,"end":154},"obj":"NCBITaxon:10088"},{"id":"T569","span":{"begin":197,"end":204},"obj":"GO:0010467"},{"id":"T570","span":{"begin":228,"end":236},"obj":"PR:000005591"},{"id":"T571","span":{"begin":237,"end":244},"obj":"SO:0001060"},{"id":"T572","span":{"begin":269,"end":279},"obj":"GO:0042571"},{"id":"T573","span":{"begin":324,"end":328},"obj":"PR:000005591"}],"text":"port [10,11].\nTo explore JNCL pathogenesis and battenin function, we previously generated a genetically precise JNCL mouse model. Cln3Δex7/8 knock-in mice harbor the ~1 kb common JNCL mutation and express a non-truncated mutant battenin isoform that is detectable with antibodies recognizing C-terminal epitopes. Homozygous Cln3"}

    craft-sa-dev

    {"project":"craft-sa-dev","denotations":[{"id":"T941","span":{"begin":5,"end":6},"obj":"-LRB-"},{"id":"T942","span":{"begin":9,"end":11},"obj":"CD"},{"id":"T943","span":{"begin":6,"end":8},"obj":"CD"},{"id":"T944","span":{"begin":8,"end":9},"obj":","},{"id":"T945","span":{"begin":11,"end":12},"obj":"-RRB-"},{"id":"T946","span":{"begin":12,"end":13},"obj":"."},{"id":"T947","span":{"begin":13,"end":129},"obj":"sentence"},{"id":"T948","span":{"begin":14,"end":16},"obj":"TO"},{"id":"T949","span":{"begin":17,"end":24},"obj":"VB"},{"id":"T950","span":{"begin":80,"end":89},"obj":"VBD"},{"id":"T951","span":{"begin":25,"end":29},"obj":"NN"},{"id":"T952","span":{"begin":30,"end":42},"obj":"NN"},{"id":"T953","span":{"begin":43,"end":46},"obj":"CC"},{"id":"T954","span":{"begin":47,"end":55},"obj":"NN"},{"id":"T955","span":{"begin":56,"end":64},"obj":"NN"},{"id":"T956","span":{"begin":64,"end":66},"obj":","},{"id":"T957","span":{"begin":66,"end":68},"obj":"PRP"},{"id":"T958","span":{"begin":69,"end":79},"obj":"RB"},{"id":"T959","span":{"begin":90,"end":91},"obj":"DT"},{"id":"T960","span":{"begin":123,"end":128},"obj":"NN"},{"id":"T961","span":{"begin":92,"end":103},"obj":"RB"},{"id":"T962","span":{"begin":104,"end":111},"obj":"JJ"},{"id":"T963","span":{"begin":112,"end":116},"obj":"NN"},{"id":"T964","span":{"begin":117,"end":122},"obj":"NN"},{"id":"T965","span":{"begin":128,"end":129},"obj":"."},{"id":"T966","span":{"begin":129,"end":312},"obj":"sentence"},{"id":"T967","span":{"begin":130,"end":138},"obj":"NN"},{"id":"T968","span":{"begin":150,"end":154},"obj":"NNS"},{"id":"T969","span":{"begin":138,"end":139},"obj":"HYPH"},{"id":"T970","span":{"begin":139,"end":140},"obj":"CD"},{"id":"T971","span":{"begin":141,"end":146},"obj":"VB"},{"id":"T972","span":{"begin":146,"end":147},"obj":"HYPH"},{"id":"T973","span":{"begin":147,"end":149},"obj":"RP"},{"id":"T974","span":{"begin":155,"end":161},"obj":"VBP"},{"id":"T975","span":{"begin":162,"end":165},"obj":"DT"},{"id":"T976","span":{"begin":184,"end":192},"obj":"NN"},{"id":"T977","span":{"begin":166,"end":167},"obj":"SYM"},{"id":"T978","span":{"begin":167,"end":168},"obj":"CD"},{"id":"T979","span":{"begin":169,"end":171},"obj":"NN"},{"id":"T980","span":{"begin":172,"end":178},"obj":"JJ"},{"id":"T981","span":{"begin":179,"end":183},"obj":"NN"},{"id":"T982","span":{"begin":193,"end":196},"obj":"CC"},{"id":"T983","span":{"begin":197,"end":204},"obj":"VBP"},{"id":"T984","span":{"begin":205,"end":206},"obj":"DT"},{"id":"T985","span":{"begin":237,"end":244},"obj":"NN"},{"id":"T986","span":{"begin":207,"end":220},"obj":"JJ"},{"id":"T987","span":{"begin":221,"end":227},"obj":"NN"},{"id":"T988","span":{"begin":228,"end":236},"obj":"NN"},{"id":"T989","span":{"begin":245,"end":249},"obj":"WDT"},{"id":"T990","span":{"begin":250,"end":252},"obj":"VBZ"},{"id":"T991","span":{"begin":253,"end":263},"obj":"JJ"},{"id":"T992","span":{"begin":264,"end":268},"obj":"IN"},{"id":"T993","span":{"begin":269,"end":279},"obj":"NNS"},{"id":"T994","span":{"begin":280,"end":291},"obj":"VBG"},{"id":"T995","span":{"begin":292,"end":293},"obj":"NN"},{"id":"T996","span":{"begin":294,"end":302},"obj":"JJ"},{"id":"T997","span":{"begin":293,"end":294},"obj":"HYPH"},{"id":"T998","span":{"begin":303,"end":311},"obj":"NNS"},{"id":"T999","span":{"begin":311,"end":312},"obj":"."},{"id":"T1001","span":{"begin":313,"end":323},"obj":"JJ"}],"relations":[{"id":"R498","pred":"punct","subj":"T941","obj":"T942"},{"id":"R500","pred":"nummod","subj":"T943","obj":"T942"},{"id":"R501","pred":"punct","subj":"T944","obj":"T942"},{"id":"R502","pred":"punct","subj":"T945","obj":"T942"},{"id":"R504","pred":"aux","subj":"T948","obj":"T949"},{"id":"R505","pred":"advcl","subj":"T949","obj":"T950"},{"id":"R506","pred":"compound","subj":"T951","obj":"T952"},{"id":"R507","pred":"dobj","subj":"T952","obj":"T949"},{"id":"R508","pred":"cc","subj":"T953","obj":"T952"},{"id":"R509","pred":"compound","subj":"T954","obj":"T955"},{"id":"R510","pred":"conj","subj":"T955","obj":"T952"},{"id":"R511","pred":"punct","subj":"T956","obj":"T950"},{"id":"R512","pred":"nsubj","subj":"T957","obj":"T950"},{"id":"R513","pred":"advmod","subj":"T958","obj":"T950"},{"id":"R514","pred":"det","subj":"T959","obj":"T960"},{"id":"R516","pred":"advmod","subj":"T961","obj":"T962"},{"id":"R517","pred":"amod","subj":"T962","obj":"T960"},{"id":"R518","pred":"compound","subj":"T963","obj":"T960"},{"id":"R519","pred":"compound","subj":"T964","obj":"T960"},{"id":"R520","pred":"punct","subj":"T965","obj":"T950"},{"id":"R521","pred":"nmod","subj":"T967","obj":"T968"},{"id":"R522","pred":"nsubj","subj":"T968","obj":"T974"},{"id":"R523","pred":"punct","subj":"T969","obj":"T967"},{"id":"R524","pred":"nummod","subj":"T970","obj":"T967"},{"id":"R525","pred":"amod","subj":"T971","obj":"T968"},{"id":"R526","pred":"punct","subj":"T972","obj":"T971"},{"id":"R527","pred":"prt","subj":"T973","obj":"T971"},{"id":"R528","pred":"det","subj":"T975","obj":"T976"},{"id":"R529","pred":"dobj","sub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[10,11].\nTo explore JNCL pathogenesis and battenin function, we previously generated a genetically precise JNCL mouse model. Cln3Δex7/8 knock-in mice harbor the ~1 kb common JNCL mutation and express a non-truncated mutant battenin isoform that is detectable with antibodies recognizing C-terminal epitopes. Homozygous Cln3"}

    craft-ca-core-ex-dev

    {"project":"craft-ca-core-ex-dev","denotations":[{"id":"T649","span":{"begin":47,"end":55},"obj":"PR_EXT:000005591"},{"id":"T650","span":{"begin":92,"end":103},"obj":"SO_EXT:0000704"},{"id":"T651","span":{"begin":117,"end":122},"obj":"NCBITaxon:10088"},{"id":"T652","span":{"begin":130,"end":134},"obj":"PR_EXT:000005591"},{"id":"T653","span":{"begin":150,"end":154},"obj":"NCBITaxon:10088"},{"id":"T654","span":{"begin":170,"end":171},"obj":"CHEBI_SO_EXT:base"},{"id":"T655","span":{"begin":184,"end":192},"obj":"SO_EXT:sequence_alteration_entity_or_process"},{"id":"T656","span":{"begin":197,"end":204},"obj":"GO:0010467"},{"id":"T657","span":{"begin":211,"end":220},"obj":"SO_EXT:sequence_truncation_process"},{"id":"T658","span":{"begin":221,"end":227},"obj":"SO_EXT:sequence_altered_entity_or_alteration_process"},{"id":"T659","span":{"begin":228,"end":236},"obj":"PR_EXT:000005591"},{"id":"T660","span":{"begin":237,"end":244},"obj":"SO_EXT:0001060"},{"id":"T661","span":{"begin":269,"end":279},"obj":"GO:0042571"},{"id":"T662","span":{"begin":292,"end":302},"obj":"CHEBI_SO_EXT:C_terminus_or_C_terminal_region"},{"id":"T663","span":{"begin":303,"end":311},"obj":"CHEBI_SO_EXT:epitope"},{"id":"T664","span":{"begin":324,"end":328},"obj":"PR_EXT:000005591"}],"text":"port [10,11].\nTo explore JNCL pathogenesis and battenin function, we previously generated a genetically precise JNCL mouse model. Cln3Δex7/8 knock-in mice harbor the ~1 kb common JNCL mutation and express a non-truncated mutant battenin isoform that is detectable with antibodies recognizing C-terminal epitopes. Homozygous Cln3"}

    2_test

    {"project":"2_test","denotations":[{"id":"15588329-10319861-12950140","span":{"begin":6,"end":8},"obj":"10319861"},{"id":"15588329-14660799-12950141","span":{"begin":9,"end":11},"obj":"14660799"}],"text":"port [10,11].\nTo explore JNCL pathogenesis and battenin function, we previously generated a genetically precise JNCL mouse model. Cln3Δex7/8 knock-in mice harbor the ~1 kb common JNCL mutation and express a non-truncated mutant battenin isoform that is detectable with antibodies recognizing C-terminal epitopes. Homozygous Cln3"}