Abbreviations 4AT Assessment test for delirium and cognitive impairment CAM Confusion Assessment Method CAM-ICU Confusion Assessment Method for the Intensive Care Unit GCS Glasgow Coma Scale ICU Intensive care unit qSOFA quick Sequential Organ Failure Assessment SOFA Sequential Organ Failure Assessment Acknowledgements This paper is dedicated to the memory of Mr. Rocco Rasulo, who died recently, a long-term sepsis survivor. Funding Not applicable. Availability of data and materials Data sharing not applicable to this article as no datasets were generated or analyzed during the current study. Authors’ contributions FAR and NL conceptualized and drafted the manuscript. GB, WEE, AM, PP reviewed and were involved in discussing and editing the manuscript. All authors read and approved the final manuscript. Competing interests The authors declare that they have no competing interests. Consent for publication The consent was obtained by the next of kin (son). Ethics approval and consent to participate Not applicable.