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PMC:523229 / 20595-22491 JSONTXT

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Id Subject Object Predicate Lexical cue
T4683 0-12 JJ denotes Interdigital
T4684 13-23 NN denotes mesenchyme
T4685 36-46 VBN denotes eliminated
T4686 24-26 VBZ denotes is
T4687 27-35 RB denotes normally
T4688 47-49 IN denotes by
T4689 50-59 NN denotes apoptosis
T4690 60-66 IN denotes during
T4691 67-76 JJ denotes embryonic
T4692 77-88 NN denotes development
T4693 88-90 , denotes ,
T4694 90-91 DT denotes a
T4695 92-99 NN denotes process
T4696 100-104 WDT denotes that
T4697 112-122 VBN denotes stimulated
T4698 105-108 MD denotes can
T4699 109-111 VB denotes be
T4700 123-125 IN denotes by
T4701 126-129 NN denotes BMP
T4702 130-135 NNS denotes beads
T4703 135-137 , denotes ,
T4704 137-146 VBN denotes inhibited
T4705 147-149 IN denotes by
T4706 150-156 NN denotes Noggin
T4707 156-158 , denotes ,
T4708 158-160 CC denotes or
T4709 161-168 VBN denotes blocked
T4710 169-171 IN denotes by
T4711 172-186 NN denotes overexpression
T4712 187-189 IN denotes of
T4713 190-198 JJ denotes dominant
T4714 199-207 JJ denotes negative
T4715 198-199 HYPH denotes -
T4716 212-221 NNS denotes receptors
T4717 208-211 NN denotes BMP
T4718 222-223 -LRB- denotes (
T4719 223-229 NNP denotes Garcia
T4720 229-230 HYPH denotes -
T4721 230-238 NNP denotes Martinez
T4722 239-241 FW denotes et
T4723 242-245 FW denotes al.
T4724 246-250 CD denotes 1993
T4725 250-251 : denotes ;
T4726 252-260 NNP denotes Yokouchi
T4727 261-263 FW denotes et
T4728 264-267 FW denotes al.
T4729 268-272 CD denotes 1996
T4730 272-273 : denotes ;
T4731 274-277 NNP denotes Zou
T4732 278-281 CC denotes and
T4733 282-291 NNP denotes Niswander
T4734 292-296 CD denotes 1996
T4735 296-297 : denotes ;
T4736 298-302 NNP denotes Guha
T4737 303-305 FW denotes et
T4738 306-309 FW denotes al.
T4739 310-314 CD denotes 2002
T4740 314-315 -RRB- denotes )
T4741 315-316 . denotes .
T4742 316-590 sentence denotes Limbs of Gdf5-Cre/Bmpr1afloxP mutant embryos showed obvious retention of interdigital webbing between the first and second, but not other, digits of E14.5 forelimbs (Figure 2A and 2B), a pattern that corresponds to the presence or absence of webbing seen in the adult limb.
T4743 317-322 NNS denotes Limbs
T4744 362-368 VBD denotes showed
T4745 323-325 IN denotes of
T4746 326-330 NN denotes Gdf5
T4747 331-334 NN denotes Cre
T4748 330-331 HYPH denotes -
T4749 335-346 NN denotes Bmpr1afloxP
T4750 334-335 HYPH denotes /
T4751 347-353 JJ denotes mutant
T4752 354-361 NNS denotes embryos
T4753 369-376 JJ denotes obvious
T4754 377-386 NN denotes retention
T4755 387-389 IN denotes of
T4756 390-402 JJ denotes interdigital
T4757 403-410 NN denotes webbing
T4758 411-418 IN denotes between
T4759 419-422 DT denotes the
T4760 456-462 NNS denotes digits
T4761 423-428 JJ denotes first
T4762 429-432 CC denotes and
T4763 433-439 JJ denotes second
T4764 439-441 , denotes ,
T4765 441-444 CC denotes but
T4766 445-448 RB denotes not
T4767 449-454 JJ denotes other
T4768 454-456 , denotes ,
T4769 463-465 IN denotes of
T4770 466-471 NN denotes E14.5
T4771 472-481 NNS denotes forelimbs
T4772 482-483 -LRB- denotes (
T4773 483-489 NN denotes Figure
T4774 490-492 CD denotes 2A
T4775 493-496 CC denotes and
T4776 497-499 CD denotes 2B
T4777 499-500 -RRB- denotes )
T4778 500-502 , denotes ,
T4779 502-503 DT denotes a
T4780 504-511 NN denotes pattern
T4781 512-516 WDT denotes that
T4782 517-528 VBZ denotes corresponds
T4783 529-531 IN denotes to
T4784 532-535 DT denotes the
T4785 536-544 NN denotes presence
T4786 545-547 CC denotes or
T4787 548-555 NN denotes absence
T4788 556-558 IN denotes of
T4789 559-566 NN denotes webbing
T4790 567-571 VBN denotes seen
T4791 572-574 IN denotes in
T4792 575-578 DT denotes the
T4793 585-589 NN denotes limb
T4794 579-584 NN denotes adult
T4795 589-590 . denotes .
T4796 590-684 sentence denotes They also showed excess tissue on the posterior margin of the fifth digit (Figure 2B, arrow).
T4797 591-595 PRP denotes They
T4798 601-607 VBD denotes showed
T4799 596-600 RB denotes also
T4800 608-614 JJ denotes excess
T4801 615-621 NN denotes tissue
T4802 622-624 IN denotes on
T4803 625-628 DT denotes the
T4804 639-645 NN denotes margin
T4805 629-638 JJ denotes posterior
T4806 646-648 IN denotes of
T4807 649-652 DT denotes the
T4808 659-664 NN denotes digit
T4809 653-658 JJ denotes fifth
T4810 665-666 -LRB- denotes (
T4811 677-682 NN denotes arrow
T4812 666-672 NN denotes Figure
T4813 673-675 CD denotes 2B
T4814 675-677 , denotes ,
T4815 682-683 -RRB- denotes )
T4816 683-684 . denotes .
T4817 684-928 sentence denotes Analysis of LACZ expression in Gdf5-Cre/R26R reporter embryos showed that Cre-mediated recombination has occurred by E13.5 in the metacarpal-phalangeal joints, and in the interdigital region between the first and second, but not other, digits.
T4818 685-693 NN denotes Analysis
T4819 747-753 VBD denotes showed
T4820 694-696 IN denotes of
T4821 697-701 NN denotes LACZ
T4822 702-712 NN denotes expression
T4823 713-715 IN denotes in
T4824 716-720 NN denotes Gdf5
T4825 721-724 NN denotes Cre
T4826 720-721 HYPH denotes -
T4827 725-729 NN denotes R26R
T4828 724-725 HYPH denotes /
T4829 739-746 NNS denotes embryos
T4830 730-738 NN denotes reporter
T4831 754-758 IN denotes that
T4832 790-798 VBN denotes occurred
T4833 759-762 NN denotes Cre
T4834 763-771 VBN denotes mediated
T4835 762-763 HYPH denotes -
T4836 772-785 NN denotes recombination
T4837 786-789 VBZ denotes has
T4838 799-801 IN denotes by
T4839 802-807 NN denotes E13.5
T4840 808-810 IN denotes in
T4841 811-814 DT denotes the
T4842 837-843 NNS denotes joints
T4843 815-825 JJ denotes metacarpal
T4844 826-836 JJ denotes phalangeal
T4845 825-826 HYPH denotes -
T4846 843-845 , denotes ,
T4847 845-848 CC denotes and
T4848 849-851 IN denotes in
T4849 852-855 DT denotes the
T4850 869-875 NN denotes region
T4851 856-868 JJ denotes interdigital
T4852 876-883 IN denotes between
T4853 884-887 DT denotes the
T4854 921-927 NNS denotes digits
T4855 888-893 JJ denotes first
T4856 894-897 CC denotes and
T4857 898-904 JJ denotes second
T4858 904-906 , denotes ,
T4859 906-909 CC denotes but
T4860 910-913 RB denotes not
T4861 914-919 JJ denotes other
T4862 919-921 , denotes ,
T4863 927-928 . denotes .
T4864 928-1070 sentence denotes In addition, a domain of recombination and expression of LACZ is also reproducibly seen in the posterior half of the fifth digit (Figure 2C).
T4865 929-931 IN denotes In
T4866 1012-1016 VBN denotes seen
T4867 932-940 NN denotes addition
T4868 940-942 , denotes ,
T4869 942-943 DT denotes a
T4870 944-950 NN denotes domain
T4871 951-953 IN denotes of
T4872 954-967 NN denotes recombination
T4873 968-971 CC denotes and
T4874 972-982 NN denotes expression
T4875 983-985 IN denotes of
T4876 986-990 NN denotes LACZ
T4877 991-993 VBZ denotes is
T4878 994-998 RB denotes also
T4879 999-1011 RB denotes reproducibly
T4880 1017-1019 IN denotes in
T4881 1020-1023 DT denotes the
T4882 1034-1038 NN denotes half
T4883 1024-1033 JJ denotes posterior
T4884 1039-1041 IN denotes of
T4885 1042-1045 DT denotes the
T4886 1052-1057 NN denotes digit
T4887 1046-1051 JJ denotes fifth
T4888 1058-1059 -LRB- denotes (
T4889 1059-1065 NN denotes Figure
T4890 1066-1068 CD denotes 2C
T4891 1068-1069 -RRB- denotes )
T4892 1069-1070 . denotes .
T4893 1070-1409 sentence denotes Terminal deoxynucleotidyl transferase–mediated deoxyuridine triphosphate nick end labeling (TUNEL) staining of interdigital mesenchyme between the first and second digits (Figure 2D and 2E) and the fifth digit flanking mesenchyme showed a decreased number of dying cells in the regions where excess tissue is retained in the mutant limbs.
T4894 1071-1079 JJ denotes Terminal
T4895 1153-1161 NN denotes labeling
T4896 1080-1096 NN denotes deoxynucleotidyl
T4897 1097-1108 NN denotes transferase
T4898 1109-1117 VBN denotes mediated
T4899 1108-1109 HYPH denotes –
T4900 1118-1130 NN denotes deoxyuridine
T4901 1131-1143 NN denotes triphosphate
T4902 1144-1148 NN denotes nick
T4903 1149-1152 NN denotes end
T4904 1170-1178 NN denotes staining
T4905 1162-1163 -LRB- denotes (
T4906 1163-1168 NN denotes TUNEL
T4907 1168-1169 -RRB- denotes )
T4908 1301-1307 VBD denotes showed
T4909 1179-1181 IN denotes of
T4910 1182-1194 JJ denotes interdigital
T4911 1195-1205 NN denotes mesenchyme
T4912 1206-1213 IN denotes between
T4913 1214-1217 DT denotes the
T4914 1235-1241 NNS denotes digits
T4915 1218-1223 JJ denotes first
T4916 1224-1227 CC denotes and
T4917 1228-1234 JJ denotes second
T4918 1242-1243 -LRB- denotes (
T4919 1243-1249 NN denotes Figure
T4920 1250-1252 CD denotes 2D
T4921 1253-1256 CC denotes and
T4922 1257-1259 CD denotes 2E
T4923 1259-1260 -RRB- denotes )
T4924 1261-1264 CC denotes and
T4925 1265-1268 DT denotes the
T4926 1275-1280 NN denotes digit
T4927 1269-1274 JJ denotes fifth
T4928 1281-1289 VBG denotes flanking
T4929 1290-1300 NN denotes mesenchyme
T4930 1308-1309 DT denotes a
T4931 1320-1326 NN denotes number
T4932 1310-1319 VBN denotes decreased
T4933 1327-1329 IN denotes of
T4934 1330-1335 VBG denotes dying
T4935 1336-1341 NNS denotes cells
T4936 1342-1344 IN denotes in
T4937 1345-1348 DT denotes the
T4938 1349-1356 NNS denotes regions
T4939 1357-1362 WRB denotes where
T4940 1380-1388 VBN denotes retained
T4941 1363-1369 JJ denotes excess
T4942 1370-1376 NN denotes tissue
T4943 1377-1379 VBZ denotes is
T4944 1389-1391 IN denotes in
T4945 1392-1395 DT denotes the
T4946 1403-1408 NNS denotes limbs
T4947 1396-1402 NN denotes mutant
T4948 1408-1409 . denotes .
T4949 1409-1523 sentence denotes Numbers of phosphorylated histone H3-labeled proliferating cells were also elevated in these regions (Figure 2F).
T4950 1410-1417 NNS denotes Numbers
T4951 1485-1493 VBN denotes elevated
T4952 1418-1420 IN denotes of
T4953 1421-1435 VBN denotes phosphorylated
T4954 1444-1446 NN denotes H3
T4955 1436-1443 NN denotes histone
T4956 1447-1454 VBN denotes labeled
T4957 1446-1447 HYPH denotes -
T4958 1469-1474 NNS denotes cells
T4959 1455-1468 VBG denotes proliferating
T4960 1475-1479 VBD denotes were
T4961 1480-1484 RB denotes also
T4962 1494-1496 IN denotes in
T4963 1497-1502 DT denotes these
T4964 1503-1510 NNS denotes regions
T4965 1511-1512 -LRB- denotes (
T4966 1512-1518 NN denotes Figure
T4967 1519-1521 CD denotes 2F
T4968 1521-1522 -RRB- denotes )
T4969 1522-1523 . denotes .
T4970 1523-1682 sentence denotes Most cells found in the webbed region between the first and second digits at E15.5 strongly expressed LACZ in Gdf5-Cre/Bmpr1afloxP mutant embryos (Figure 2H).
T4971 1524-1528 JJS denotes Most
T4972 1529-1534 NNS denotes cells
T4973 1616-1625 VBD denotes expressed
T4974 1535-1540 VBN denotes found
T4975 1541-1543 IN denotes in
T4976 1544-1547 DT denotes the
T4977 1555-1561 NN denotes region
T4978 1548-1554 VBN denotes webbed
T4979 1562-1569 IN denotes between
T4980 1570-1573 DT denotes the
T4981 1591-1597 NNS denotes digits
T4982 1574-1579 JJ denotes first
T4983 1580-1583 CC denotes and
T4984 1584-1590 JJ denotes second
T4985 1598-1600 IN denotes at
T4986 1601-1606 NN denotes E15.5
T4987 1607-1615 RB denotes strongly
T4988 1626-1630 NN denotes LACZ
T4989 1631-1633 IN denotes in
T4990 1634-1638 NN denotes Gdf5
T4991 1639-1642 NN denotes Cre
T4992 1638-1639 HYPH denotes -
T4993 1643-1654 NN denotes Bmpr1afloxP
T4994 1642-1643 HYPH denotes /
T4995 1662-1669 NNS denotes embryos
T4996 1655-1661 NN denotes mutant
T4997 1670-1671 -LRB- denotes (
T4998 1671-1677 NN denotes Figure
T4999 1678-1680 CD denotes 2H
T5000 1680-1681 -RRB- denotes )
T5001 1681-1682 . denotes .
T5002 1682-1896 sentence denotes These data suggest that regional loss of BMPR1A receptor signaling blocks programmed cell death in interdigital mesenchyme, and that the recombined cells survive and proliferate in the absence of BMPR1A signaling.
T5003 1683-1688 DT denotes These
T5004 1689-1693 NNS denotes data
T5005 1694-1701 VBP denotes suggest
T5006 1702-1706 IN denotes that
T5007 1750-1756 VBZ denotes blocks
T5008 1707-1715 JJ denotes regional
T5009 1716-1720 NN denotes loss
T5010 1721-1723 IN denotes of
T5011 1724-1730 NN denotes BMPR1A
T5012 1740-1749 NN denotes signaling
T5013 1731-1739 NN denotes receptor
T5014 1757-1767 VBN denotes programmed
T5015 1773-1778 NN denotes death
T5016 1768-1772 NN denotes cell
T5017 1779-1781 IN denotes in
T5018 1782-1794 JJ denotes interdigital
T5019 1795-1805 NN denotes mesenchyme
T5020 1805-1807 , denotes ,
T5021 1807-1810 CC denotes and
T5022 1811-1815 IN denotes that
T5023 1837-1844 VBP denotes survive
T5024 1816-1819 DT denotes the
T5025 1831-1836 NNS denotes cells
T5026 1820-1830 VBN denotes recombined
T5027 1845-1848 CC denotes and
T5028 1849-1860 VBP denotes proliferate
T5029 1861-1863 IN denotes in
T5030 1864-1867 DT denotes the
T5031 1868-1875 NN denotes absence
T5032 1876-1878 IN denotes of
T5033 1879-1885 NN denotes BMPR1A
T5034 1886-1895 NN denotes signaling
T5035 1895-1896 . denotes .
R2950 T4683 T4684 amod Interdigital,mesenchyme
R2951 T4684 T4685 nsubjpass mesenchyme,eliminated
R2952 T4686 T4685 auxpass is,eliminated
R2953 T4687 T4685 advmod normally,eliminated
R2954 T4688 T4685 agent by,eliminated
R2955 T4689 T4688 pobj apoptosis,by
R2956 T4690 T4685 prep during,eliminated
R2957 T4691 T4692 amod embryonic,development
R2958 T4692 T4690 pobj development,during
R2959 T4693 T4685 punct ", ",eliminated
R2960 T4694 T4695 det a,process
R2961 T4695 T4685 npadvmod process,eliminated
R2962 T4696 T4697 dep that,stimulated
R2963 T4697 T4695 relcl stimulated,process
R2964 T4698 T4697 aux can,stimulated
R2965 T4699 T4697 auxpass be,stimulated
R2966 T4700 T4697 agent by,stimulated
R2967 T4701 T4702 compound BMP,beads
R2968 T4702 T4700 pobj beads,by
R2969 T4703 T4697 punct ", ",stimulated
R2970 T4704 T4697 conj inhibited,stimulated
R2971 T4705 T4704 agent by,inhibited
R2972 T4706 T4705 pobj Noggin,by
R2973 T4707 T4704 punct ", ",inhibited
R2974 T4708 T4704 cc or,inhibited
R2975 T4709 T4704 conj blocked,inhibited
R2976 T4710 T4709 agent by,blocked
R2977 T4711 T4710 pobj overexpression,by
R2978 T4712 T4711 prep of,overexpression
R2979 T4713 T4714 amod dominant,negative
R2980 T4714 T4716 nmod negative,receptors
R2981 T4715 T4714 punct -,negative
R2982 T4716 T4712 pobj receptors,of
R2983 T4717 T4716 compound BMP,receptors
R2984 T4718 T4719 punct (,Garcia
R2985 T4719 T4685 meta Garcia,eliminated
R2986 T4720 T4719 punct -,Garcia
R2987 T4721 T4719 nmod Martinez,Garcia
R2988 T4722 T4719 nmod et,Garcia
R2989 T4723 T4719 nmod al.,Garcia
R2990 T4724 T4719 nummod 1993,Garcia
R2991 T4725 T4719 punct ;,Garcia
R2992 T4726 T4719 conj Yokouchi,Garcia
R2993 T4727 T4726 nmod et,Yokouchi
R2994 T4728 T4726 nmod al.,Yokouchi
R2995 T4729 T4726 nummod 1996,Yokouchi
R2996 T4730 T4726 punct ;,Yokouchi
R2997 T4731 T4726 conj Zou,Yokouchi
R2998 T4732 T4731 cc and,Zou
R2999 T4733 T4731 conj Niswander,Zou
R3000 T4734 T4733 nummod 1996,Niswander
R3001 T4735 T4733 punct ;,Niswander
R3002 T4736 T4733 conj Guha,Niswander
R3003 T4737 T4736 nmod et,Guha
R3004 T4738 T4736 nmod al.,Guha
R3005 T4739 T4736 nummod 2002,Guha
R3006 T4740 T4736 punct ),Guha
R3007 T4741 T4685 punct .,eliminated
R3008 T4743 T4744 nsubj Limbs,showed
R3009 T4745 T4743 prep of,Limbs
R3010 T4746 T4747 compound Gdf5,Cre
R3011 T4747 T4749 compound Cre,Bmpr1afloxP
R3012 T4748 T4747 punct -,Cre
R3013 T4749 T4751 npadvmod Bmpr1afloxP,mutant
R3014 T4750 T4749 punct /,Bmpr1afloxP
R3015 T4751 T4752 amod mutant,embryos
R3016 T4752 T4745 pobj embryos,of
R3017 T4753 T4754 amod obvious,retention
R3018 T4754 T4744 dobj retention,showed
R3019 T4755 T4754 prep of,retention
R3020 T4756 T4757 amod interdigital,webbing
R3021 T4757 T4755 pobj webbing,of
R3022 T4758 T4757 prep between,webbing
R3023 T4759 T4760 det the,digits
R3024 T4760 T4758 pobj digits,between
R3025 T4761 T4760 amod first,digits
R3026 T4762 T4761 cc and,first
R3027 T4763 T4761 conj second,first
R3028 T4764 T4761 punct ", ",first
R3029 T4765 T4761 cc but,first
R3030 T4766 T4765 neg not,but
R3031 T4767 T4761 conj other,first
R3032 T4768 T4760 punct ", ",digits
R3033 T4769 T4760 prep of,digits
R3034 T4770 T4771 compound E14.5,forelimbs
R3035 T4771 T4769 pobj forelimbs,of
R3036 T4772 T4773 punct (,Figure
R3037 T4773 T4760 parataxis Figure,digits
R3038 T4774 T4773 nummod 2A,Figure
R3039 T4775 T4773 cc and,Figure
R3040 T4776 T4773 conj 2B,Figure
R3041 T4777 T4773 punct ),Figure
R3042 T4778 T4744 punct ", ",showed
R3043 T4779 T4780 det a,pattern
R3044 T4780 T4744 npadvmod pattern,showed
R3045 T4781 T4782 dep that,corresponds
R3046 T4782 T4780 relcl corresponds,pattern
R3047 T4783 T4782 prep to,corresponds
R3048 T4784 T4785 det the,presence
R3049 T4785 T4783 pobj presence,to
R3050 T4786 T4785 cc or,presence
R3051 T4787 T4785 conj absence,presence
R3052 T4788 T4785 prep of,presence
R3053 T4789 T4788 pobj webbing,of
R3054 T4790 T4789 acl seen,webbing
R3055 T4791 T4790 prep in,seen
R3056 T4792 T4793 det the,limb
R3057 T4793 T4791 pobj limb,in
R3058 T4794 T4793 compound adult,limb
R3059 T4795 T4744 punct .,showed
R3060 T4797 T4798 nsubj They,showed
R3061 T4799 T4798 advmod also,showed
R3062 T4800 T4801 amod excess,tissue
R3063 T4801 T4798 dobj tissue,showed
R3064 T4802 T4798 prep on,showed
R3065 T4803 T4804 det the,margin
R3066 T4804 T4802 pobj margin,on
R3067 T4805 T4804 amod posterior,margin
R3068 T4806 T4804 prep of,margin
R3069 T4807 T4808 det the,digit
R3070 T4808 T4806 pobj digit,of
R3071 T4809 T4808 amod fifth,digit
R3072 T4810 T4811 punct (,arrow
R3073 T4811 T4798 parataxis arrow,showed
R3074 T4812 T4811 dep Figure,arrow
R3075 T4813 T4812 nummod 2B,Figure
R3076 T4814 T4811 punct ", ",arrow
R3077 T4815 T4811 punct ),arrow
R3078 T4816 T4798 punct .,showed
R3079 T4818 T4819 nsubj Analysis,showed
R3080 T4820 T4818 prep of,Analysis
R3081 T4821 T4822 compound LACZ,expression
R3082 T4822 T4820 pobj expression,of
R3083 T4823 T4818 prep in,Analysis
R3084 T4824 T4825 compound Gdf5,Cre
R3085 T4825 T4827 compound Cre,R26R
R3086 T4826 T4825 punct -,Cre
R3087 T4827 T4829 compound R26R,embryos
R3088 T4828 T4827 punct /,R26R
R3089 T4829 T4823 pobj embryos,in
R3090 T4830 T4829 compound reporter,embryos
R3091 T4831 T4832 mark that,occurred
R3092 T4832 T4819 ccomp occurred,showed
R3093 T4833 T4834 npadvmod Cre,mediated
R3094 T4834 T4836 amod mediated,recombination
R3095 T4835 T4834 punct -,mediated
R3096 T4836 T4832 nsubj recombination,occurred
R3097 T4837 T4832 aux has,occurred
R3098 T4838 T4832 prep by,occurred
R3099 T4839 T4838 pobj E13.5,by
R3100 T4840 T4832 prep in,occurred
R3101 T4841 T4842 det the,joints
R3102 T4842 T4840 pobj joints,in
R3103 T4843 T4844 amod metacarpal,phalangeal
R3104 T4844 T4842 amod phalangeal,joints
R3105 T4845 T4844 punct -,phalangeal
R3106 T4846 T4840 punct ", ",in
R3107 T4847 T4840 cc and,in
R3108 T4848 T4840 conj in,in
R3109 T4849 T4850 det the,region
R3110 T4850 T4848 pobj region,in
R3111 T4851 T4850 amod interdigital,region
R3112 T4852 T4850 prep between,region
R3113 T4853 T4854 det the,digits
R3114 T4854 T4852 pobj digits,between
R3115 T4855 T4854 amod first,digits
R3116 T4856 T4855 cc and,first
R3117 T4857 T4855 conj second,first
R3118 T4858 T4855 punct ", ",first
R3119 T4859 T4855 cc but,first
R3120 T4860 T4859 neg not,but
R3121 T4861 T4855 conj other,first
R3122 T4862 T4854 punct ", ",digits
R3123 T4863 T4819 punct .,showed
R3124 T4865 T4866 prep In,seen
R3125 T4867 T4865 pobj addition,In
R3126 T4868 T4866 punct ", ",seen
R3127 T4869 T4870 det a,domain
R3128 T4870 T4866 nsubjpass domain,seen
R3129 T4871 T4870 prep of,domain
R3130 T4872 T4871 pobj recombination,of
R3131 T4873 T4872 cc and,recombination
R3132 T4874 T4872 conj expression,recombination
R3133 T4875 T4872 prep of,recombination
R3134 T4876 T4875 pobj LACZ,of
R3135 T4877 T4866 auxpass is,seen
R3136 T4878 T4866 advmod also,seen
R3137 T4879 T4866 advmod reproducibly,seen
R3138 T4880 T4866 prep in,seen
R3139 T4881 T4882 det the,half
R3140 T4882 T4880 pobj half,in
R3141 T4883 T4882 amod posterior,half
R3142 T4884 T4882 prep of,half
R3143 T4885 T4886 det the,digit
R3144 T4886 T4884 pobj digit,of
R3145 T4887 T4886 amod fifth,digit
R3146 T4888 T4889 punct (,Figure
R3147 T4889 T4866 parataxis Figure,seen
R3148 T4890 T4889 nummod 2C,Figure
R3149 T4891 T4889 punct ),Figure
R3150 T4892 T4866 punct .,seen
R3151 T4894 T4895 amod Terminal,labeling
R3152 T4895 T4904 nmod labeling,staining
R3153 T4896 T4897 compound deoxynucleotidyl,transferase
R3154 T4897 T4898 npadvmod transferase,mediated
R3155 T4898 T4895 amod mediated,labeling
R3156 T4899 T4898 punct –,mediated
R3157 T4900 T4901 nmod deoxyuridine,triphosphate
R3158 T4901 T4895 nmod triphosphate,labeling
R3159 T4902 T4903 nmod nick,end
R3160 T4903 T4895 nmod end,labeling
R3161 T4904 T4908 nsubj staining,showed
R3162 T4905 T4906 punct (,TUNEL
R3163 T4906 T4895 appos TUNEL,labeling
R3164 T4907 T4906 punct ),TUNEL
R3165 T4909 T4904 prep of,staining
R3166 T4910 T4911 amod interdigital,mesenchyme
R3167 T4911 T4909 pobj mesenchyme,of
R3168 T4912 T4911 prep between,mesenchyme
R3169 T4913 T4914 det the,digits
R3170 T4914 T4912 pobj digits,between
R3171 T4915 T4914 amod first,digits
R3172 T4916 T4915 cc and,first
R3173 T4917 T4915 conj second,first
R3174 T4918 T4919 punct (,Figure
R3175 T4919 T4914 parataxis Figure,digits
R3176 T4920 T4919 nummod 2D,Figure
R3177 T4921 T4919 cc and,Figure
R3178 T4922 T4919 conj 2E,Figure
R3179 T4923 T4919 punct ),Figure
R3180 T4924 T4914 cc and,digits
R3181 T4925 T4926 det the,digit
R3182 T4926 T4914 conj digit,digits
R3183 T4927 T4926 amod fifth,digit
R3184 T4928 T4914 acl flanking,digits
R3185 T4929 T4928 dobj mesenchyme,flanking
R3186 T4930 T4931 det a,number
R3187 T4931 T4908 dobj number,showed
R3188 T4932 T4931 amod decreased,number
R3189 T4933 T4931 prep of,number
R3190 T4934 T4935 amod dying,cells
R3191 T4935 T4933 pobj cells,of
R3192 T4936 T4908 prep in,showed
R3193 T4937 T4938 det the,regions
R3194 T4938 T4936 pobj regions,in
R3195 T4939 T4940 advmod where,retained
R3196 T4940 T4938 relcl retained,regions
R3197 T4941 T4942 amod excess,tissue
R3198 T4942 T4940 nsubjpass tissue,retained
R3199 T4943 T4940 auxpass is,retained
R3200 T4944 T4940 prep in,retained
R3201 T4945 T4946 det the,limbs
R3202 T4946 T4944 pobj limbs,in
R3203 T4947 T4946 compound mutant,limbs
R3204 T4948 T4908 punct .,showed
R3205 T4950 T4951 nsubjpass Numbers,elevated
R3206 T4952 T4950 prep of,Numbers
R3207 T4953 T4954 amod phosphorylated,H3
R3208 T4954 T4956 npadvmod H3,labeled
R3209 T4955 T4954 compound histone,H3
R3210 T4956 T4958 amod labeled,cells
R3211 T4957 T4956 punct -,labeled
R3212 T4958 T4952 pobj cells,of
R3213 T4959 T4958 amod proliferating,cells
R3214 T4960 T4951 auxpass were,elevated
R3215 T4961 T4951 advmod also,elevated
R3216 T4962 T4951 prep in,elevated
R3217 T4963 T4964 det these,regions
R3218 T4964 T4962 pobj regions,in
R3219 T4965 T4966 punct (,Figure
R3220 T4966 T4951 parataxis Figure,elevated
R3221 T4967 T4966 nummod 2F,Figure
R3222 T4968 T4966 punct ),Figure
R3223 T4969 T4951 punct .,elevated
R3224 T4971 T4972 amod Most,cells
R3225 T4972 T4973 nsubj cells,expressed
R3226 T4974 T4972 acl found,cells
R3227 T4975 T4974 prep in,found
R3228 T4976 T4977 det the,region
R3229 T4977 T4975 pobj region,in
R3230 T4978 T4977 amod webbed,region
R3231 T4979 T4977 prep between,region
R3232 T4980 T4981 det the,digits
R3233 T4981 T4979 pobj digits,between
R3234 T4982 T4981 amod first,digits
R3235 T4983 T4982 cc and,first
R3236 T4984 T4982 conj second,first
R3237 T4985 T4974 prep at,found
R3238 T4986 T4985 pobj E15.5,at
R3239 T4987 T4973 advmod strongly,expressed
R3240 T4988 T4973 dobj LACZ,expressed
R3241 T4989 T4973 prep in,expressed
R3242 T4990 T4991 compound Gdf5,Cre
R3243 T4991 T4993 compound Cre,Bmpr1afloxP
R3244 T4992 T4991 punct -,Cre
R3245 T4993 T4995 compound Bmpr1afloxP,embryos
R3246 T4994 T4993 punct /,Bmpr1afloxP
R3247 T4995 T4989 pobj embryos,in
R3248 T4996 T4995 compound mutant,embryos
R3249 T4997 T4998 punct (,Figure
R3250 T4998 T4973 parataxis Figure,expressed
R3251 T4999 T4998 nummod 2H,Figure
R3252 T5000 T4998 punct ),Figure
R3253 T5001 T4973 punct .,expressed
R3254 T5003 T5004 det These,data
R3255 T5004 T5005 nsubj data,suggest
R3256 T5006 T5007 mark that,blocks
R3257 T5007 T5005 advcl blocks,suggest
R3258 T5008 T5009 amod regional,loss
R3259 T5009 T5007 nsubj loss,blocks
R3260 T5010 T5009 prep of,loss
R3261 T5011 T5012 compound BMPR1A,signaling
R3262 T5012 T5010 pobj signaling,of
R3263 T5013 T5012 compound receptor,signaling
R3264 T5014 T5015 amod programmed,death
R3265 T5015 T5007 dobj death,blocks
R3266 T5016 T5015 compound cell,death
R3267 T5017 T5007 prep in,blocks
R3268 T5018 T5019 amod interdigital,mesenchyme
R3269 T5019 T5017 pobj mesenchyme,in
R3270 T5020 T5007 punct ", ",blocks
R3271 T5021 T5007 cc and,blocks
R3272 T5022 T5023 mark that,survive
R3273 T5023 T5007 conj survive,blocks
R3274 T5024 T5025 det the,cells
R3275 T5025 T5023 nsubj cells,survive
R3276 T5026 T5025 amod recombined,cells
R3277 T5027 T5023 cc and,survive
R3278 T5028 T5023 conj proliferate,survive
R3279 T5029 T5028 prep in,proliferate
R3280 T5030 T5031 det the,absence
R3281 T5031 T5029 pobj absence,in
R3282 T5032 T5031 prep of,absence
R3283 T5033 T5034 compound BMPR1A,signaling
R3284 T5034 T5032 pobj signaling,of
R3285 T5035 T5005 punct .,suggest

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T4595 0-23 UBERON:0009585 denotes Interdigital mesenchyme
T4596 36-46 GO_EXT:killing denotes eliminated
T4597 50-59 GO:0006915 denotes apoptosis
T4598 67-76 UBERON:0000922 denotes embryonic
T4599 67-88 GO:0009790 denotes embryonic development
T4600 126-129 PR_EXT:000000034 denotes BMP
T4601 150-156 PR_EXT:000000021 denotes Noggin
T4602 176-186 GO:0010467 denotes expression
T4603 208-211 PR_EXT:000000034 denotes BMP
T4604 208-221 GO_EXT:0098821 denotes BMP receptors
T4605 317-322 UBERON:0002101 denotes Limbs
T4606 326-330 PR_EXT:000000281 denotes Gdf5
T4607 335-341 PR_EXT:000000035 denotes Bmpr1a
T4608 341-346 SO:0000359 denotes floxP
T4609 347-353 SO_EXT:sequence_altered_entity_or_alteration_process denotes mutant
T4611 390-410 UBERON:0006015 denotes interdigital webbing
T4612 423-428 _FRAGMENT denotes first
T4613 456-465 _FRAGMENT denotes digits of
T4614 472-481 UBERON:0001463 denotes forelimbs
T4615 433-439 _FRAGMENT denotes second
T4616 472-481 UBERON:0003622 denotes forelimbs
T4617 579-584 UBERON:0007023 denotes adult
T4618 585-589 UBERON:0002101 denotes limb
T4619 615-621 UBERON:0000479 denotes tissue
T4620 653-664 UBERON:0006052 denotes fifth digit
T4621 697-701 PR_EXT:000033987 denotes LACZ
T4622 702-712 GO:0010467 denotes expression
T4623 716-720 PR_EXT:000000281 denotes Gdf5
T4624 739-746 UBERON:0000922 denotes embryos
T4625 772-785 GO_SO_EXT:sequence_rearrangement_process denotes recombination
T4626 815-843 UBERON:0003695 denotes metacarpal-phalangeal joints
T4627 856-883 _FRAGMENT denotes interdigital region between
T4628 888-904 _FRAGMENT denotes first and second
T4629 921-927 UBERON:0006016 denotes digits
T4630 954-967 GO_SO_EXT:sequence_rearrangement_process denotes recombination
T4631 972-982 GO:0010467 denotes expression
T4632 986-990 PR_EXT:000033987 denotes LACZ
T4633 1046-1057 UBERON:0006052 denotes fifth digit
T4634 1071-1108 GO_PR_EXT:DNA_nucleotidylexotransferase denotes Terminal deoxynucleotidyl transferase
T4635 1080-1096 CHEBI_SO_EXT:deoxyribonucleotide denotes deoxynucleotidyl
T4636 1118-1143 CHEBI_EXT:dUTP denotes deoxyuridine triphosphate
T4637 1153-1161 CHEBI_SO_EXT:molecular_label_or_mark_or_tag_process denotes labeling
T4638 1182-1213 _FRAGMENT denotes interdigital mesenchyme between
T4639 1218-1241 UBERON:0009596 denotes first and second digits
T4640 1269-1280 UBERON:0006052 denotes fifth digit
T4641 1290-1300 UBERON:0003104 denotes mesenchyme
T4642 1330-1335 GO:0016265 denotes dying
T4643 1336-1341 CL_GO_EXT:cell denotes cells
T4644 1370-1376 UBERON:0000479 denotes tissue
T4645 1396-1402 SO_EXT:sequence_altered_entity_or_alteration_process denotes mutant
T4646 1403-1408 UBERON:0002101 denotes limbs
T4647 1421-1435 GO_PATO_EXT:phosphorylation_process_or_quality denotes phosphorylated
T4648 1436-1443 CHEBI:15358 denotes histone
T4649 1436-1446 PR_EXT:000027594 denotes histone H3
T4650 1447-1454 CHEBI_SO_EXT:molecular_label_or_mark_or_tag_process denotes labeled
T4651 1455-1468 GO:0008283 denotes proliferating
T4652 1469-1474 CL_GO_EXT:cell denotes cells
T4653 1529-1534 CL_GO_EXT:cell denotes cells
T4654 1548-1569 _FRAGMENT denotes webbed region between
T4655 1591-1597 UBERON:0006015 denotes digits
T4656 1574-1579 _FRAGMENT denotes first
T4657 1591-1597 UBERON:0006048 denotes digits
T4658 1584-1597 UBERON:0006049 denotes second digits
T4659 1616-1625 GO:0010467 denotes expressed
T4660 1626-1630 PR_EXT:000033987 denotes LACZ
T4661 1634-1638 PR_EXT:000000281 denotes Gdf5
T4662 1643-1649 PR_EXT:000000035 denotes Bmpr1a
T4663 1649-1654 SO:0000359 denotes floxP
T4664 1655-1661 SO_EXT:sequence_altered_entity_or_alteration_process denotes mutant
T4665 1662-1669 UBERON:0000922 denotes embryos
T4666 1724-1730 PR_EXT:000000035 denotes BMPR1A
T4667 1731-1739 GO_EXT:0004872 denotes receptor
T4668 1740-1749 GO_EXT:cell_communication_or_signaling_or_signal_transduction denotes signaling
T4669 1757-1778 GO:0012501 denotes programmed cell death
T4670 1768-1772 CL_GO_EXT:cell denotes cell
T4671 1782-1805 UBERON:0009585 denotes interdigital mesenchyme
T4672 1820-1830 GO_SO_EXT:sequence_rearrangement_process denotes recombined
T4673 1831-1836 CL_GO_EXT:cell denotes cells
T4674 1849-1860 GO:0008283 denotes proliferate
T4675 1879-1885 PR_EXT:000000035 denotes BMPR1A
T4676 1886-1895 GO_EXT:cell_communication_or_signaling_or_signal_transduction denotes signaling
T4610 354-361 UBERON:0000922 denotes embryos
R2937 T4613 T4612 _lexicallyChainedTo digits of,first
R2938 T4613 T4615 _lexicallyChainedTo digits of,second
R2939 T4614 T4613 _lexicallyChainedTo forelimbs,digits of
R2940 T4616 T4613 _lexicallyChainedTo forelimbs,digits of
R2941 T4628 T4627 _lexicallyChainedTo first and second,interdigital region between
R2942 T4629 T4628 _lexicallyChainedTo digits,first and second
R2943 T4639 T4638 _lexicallyChainedTo first and second digits,interdigital mesenchyme between
R2944 T4655 T4654 _lexicallyChainedTo digits,webbed region between
R2945 T4657 T4656 _lexicallyChainedTo digits,first

craft-ca-core-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T4535 0-23 UBERON:0009585 denotes Interdigital mesenchyme
T4536 50-59 GO:0006915 denotes apoptosis
T4537 67-76 UBERON:0000922 denotes embryonic
T4538 67-88 GO:0009790 denotes embryonic development
T4539 126-129 PR:000000034 denotes BMP
T4540 150-156 PR:000000021 denotes Noggin
T4541 176-186 GO:0010467 denotes expression
T4542 208-211 PR:000000034 denotes BMP
T4543 317-322 UBERON:0002101 denotes Limbs
T4544 326-330 PR:000000281 denotes Gdf5
T4545 335-341 PR:000000035 denotes Bmpr1a
T4546 341-346 SO:0000359 denotes floxP
T4547 354-361 UBERON:0000922 denotes embryos
T4548 390-410 UBERON:0006015 denotes interdigital webbing
T4549 423-428 _FRAGMENT denotes first
T4550 456-465 _FRAGMENT denotes digits of
T4551 472-481 UBERON:0001463 denotes forelimbs
T4552 433-439 _FRAGMENT denotes second
T4553 472-481 UBERON:0003622 denotes forelimbs
T4554 579-584 UBERON:0007023 denotes adult
T4555 585-589 UBERON:0002101 denotes limb
T4556 615-621 UBERON:0000479 denotes tissue
T4557 653-664 UBERON:0006052 denotes fifth digit
T4558 697-701 PR:000033987 denotes LACZ
T4559 702-712 GO:0010467 denotes expression
T4560 716-720 PR:000000281 denotes Gdf5
T4561 739-746 UBERON:0000922 denotes embryos
T4562 815-843 UBERON:0003695 denotes metacarpal-phalangeal joints
T4563 856-883 _FRAGMENT denotes interdigital region between
T4564 888-904 _FRAGMENT denotes first and second
T4565 921-927 UBERON:0006016 denotes digits
T4566 972-982 GO:0010467 denotes expression
T4567 986-990 PR:000033987 denotes LACZ
T4568 1046-1057 UBERON:0006052 denotes fifth digit
T4569 1182-1213 _FRAGMENT denotes interdigital mesenchyme between
T4570 1218-1241 UBERON:0009596 denotes first and second digits
T4571 1269-1280 UBERON:0006052 denotes fifth digit
T4572 1290-1300 UBERON:0003104 denotes mesenchyme
T4573 1330-1335 GO:0016265 denotes dying
T4574 1370-1376 UBERON:0000479 denotes tissue
T4575 1403-1408 UBERON:0002101 denotes limbs
T4576 1436-1443 CHEBI:15358 denotes histone
T4577 1436-1446 PR:000027594 denotes histone H3
T4578 1455-1468 GO:0008283 denotes proliferating
T4579 1548-1569 _FRAGMENT denotes webbed region between
T4580 1591-1597 UBERON:0006015 denotes digits
T4581 1574-1579 _FRAGMENT denotes first
T4582 1591-1597 UBERON:0006048 denotes digits
T4583 1584-1597 UBERON:0006049 denotes second digits
T4584 1616-1625 GO:0010467 denotes expressed
T4585 1626-1630 PR:000033987 denotes LACZ
T4586 1634-1638 PR:000000281 denotes Gdf5
T4587 1643-1649 PR:000000035 denotes Bmpr1a
T4588 1649-1654 SO:0000359 denotes floxP
T4589 1662-1669 UBERON:0000922 denotes embryos
T4590 1724-1730 PR:000000035 denotes BMPR1A
T4591 1757-1778 GO:0012501 denotes programmed cell death
T4592 1782-1805 UBERON:0009585 denotes interdigital mesenchyme
T4593 1849-1860 GO:0008283 denotes proliferate
T4594 1879-1885 PR:000000035 denotes BMPR1A
R2928 T4550 T4549 _lexicallyChainedTo digits of,first
R2929 T4550 T4552 _lexicallyChainedTo digits of,second
R2930 T4551 T4550 _lexicallyChainedTo forelimbs,digits of
R2931 T4553 T4550 _lexicallyChainedTo forelimbs,digits of
R2932 T4564 T4563 _lexicallyChainedTo first and second,interdigital region between
R2933 T4565 T4564 _lexicallyChainedTo digits,first and second
R2934 T4570 T4569 _lexicallyChainedTo first and second digits,interdigital mesenchyme between
R2935 T4580 T4579 _lexicallyChainedTo digits,webbed region between
R2936 T4582 T4581 _lexicallyChainedTo digits,first

2_test

Id Subject Object Predicate Lexical cue
15492776-8270624-84887311 246-250 8270624 denotes 1993
15492776-9012494-84887312 268-272 9012494 denotes 1996
15492776-8614838-84887313 292-296 8614838 denotes 1996
15492776-12217322-84887314 310-314 12217322 denotes 2002
T80418 246-250 8270624 denotes 1993
T21180 268-272 9012494 denotes 1996
T13954 292-296 8614838 denotes 1996
T30694 310-314 12217322 denotes 2002