BMP Receptor Signaling Is Required for Postnatal Maintenance of Articular Cartilage
Joint-Specific Knockout of Bmpr1a

Abstract
Articular cartilage plays an essential role in health and mobility, but is frequently damaged or lost in millions of people that develop arthritis. The molecular mechanisms that create and maintain this thin layer of cartilage that covers the surface of bones in joint regions are poorly understood, in part because tools to manipulate gene express