Amylin (or islet amyloid polypeptide, IAPP), a hormone co-secreted with insulin from pancreatic β-cells, inhibits feeding in mammals (Riediger et al., 2003). In fish, the role of amylin in feeding has only been examined in goldfish. In this species, IP or ICV amylin treatments decrease food intake whereas ICV injections of an amylin receptor antagonist (AC 187) stimulate feeding (Thavanathan and Volkoff, 2006), suggesting an anorexigenic role for amylin in fish.