PMC:5126056 / 4682-6008 JSONTXT

{"project":"0_colil","denotations":[{"id":"27965528-24795698-246292","span":{"begin":85,"end":89},"obj":"24795698"}],"text":"Overview of regulation of food intake\nIn fish, as in mammals (Sobrino Crespo et al., 2014), feeding behavior is regulated by specific regions in the brain, the so-called feeding centers. Early pioneer studies using stimulation and lesion experiments in teleosts (reviewed in Peter, 1979) and elasmobranchs (reviewed in Demski, 2012) seemed to indicate that the hypothalamic area was involved in feeding and that the brain control of feeding in fish might use mechanisms similar to those in mammals. However, whereas in mammals, the feeding centers appear to be restricted to the hypothalamus, evidence indicates that they might be more widespread in fish brains (Cerda-Reverter and Canosa, 2009).\nFeeding centers are under the influence of hormones produced by the brain and the periphery. Neurohormones secreted by the brain, in particular the hypothalamic area, regulate energy balance by inhibiting (anorexigenic factors) or stimulating (orexigenic factors) feeding. Peripheral chemical (e.g., glucose) or endocrine (e.g., gastrointestinal hormones) factors released in the blood cross the blood brain barrier and have a direct action on feeding centers. Peripheral sensory information (mechanical or endocrine) carried by the vagus nerve can also affect feeding centers, via innervation from the brainstem (Volkoff, 2011)."}

{"project":"2_test","denotations":[{"id":"27965528-24795698-38190226","span":{"begin":85,"end":89},"obj":"24795698"}],"text":"Overview of regulation of food intake\nIn fish, as in mammals (Sobrino Crespo et al., 2014), feeding behavior is regulated by specific regions in the brain, the so-called feeding centers. Early pioneer studies using stimulation and lesion experiments in teleosts (reviewed in Peter, 1979) and elasmobranchs (reviewed in Demski, 2012) seemed to indicate that the hypothalamic area was involved in feeding and that the brain control of feeding in fish might use mechanisms similar to those in mammals. However, whereas in mammals, the feeding centers appear to be restricted to the hypothalamus, evidence indicates that they might be more widespread in fish brains (Cerda-Reverter and Canosa, 2009).\nFeeding centers are under the influence of hormones produced by the brain and the periphery. Neurohormones secreted by the brain, in particular the hypothalamic area, regulate energy balance by inhibiting (anorexigenic factors) or stimulating (orexigenic factors) feeding. Peripheral chemical (e.g., glucose) or endocrine (e.g., gastrointestinal hormones) factors released in the blood cross the blood brain barrier and have a direct action on feeding centers. Peripheral sensory information (mechanical or endocrine) carried by the vagus nerve can also affect feeding centers, via innervation from the brainstem (Volkoff, 2011)."}