PMC:5097349 / 2171-2806 JSONTXT

{"project":"AxD_symptoms","denotations":[{"id":"T6","span":{"begin":214,"end":227},"obj":"Phenotype"},{"id":"T7","span":{"begin":487,"end":493},"obj":"Phenotype"},{"id":"T8","span":{"begin":495,"end":505},"obj":"Phenotype"},{"id":"T9","span":{"begin":507,"end":517},"obj":"Phenotype"},{"id":"T10","span":{"begin":605,"end":619},"obj":"Phenotype"}],"attributes":[{"id":"A6","pred":"hp_id","subj":"T6","obj":"http://purl.obolibrary.org/obo/HP_0003690"},{"id":"A7","pred":"hp_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/HP_0001251"},{"id":"A8","pred":"hp_id","subj":"T8","obj":"http://purl.obolibrary.org/obo/HP_0001260"},{"id":"A9","pred":"hp_id","subj":"T9","obj":"http://purl.obolibrary.org/obo/HP_0000716"},{"id":"A10","pred":"hp_id","subj":"T10","obj":"http://purl.obolibrary.org/obo/HP_0003202"}],"text":"A 34-year-old female was evaluated at our hospital with a 6-year history of progressive neurological symptoms. At age 28, she developed paroxysmal numbness in the left limbs, and two years later she had unilateral limb weakness. She was misdiagnosed as multiple sclerosis at the other hospital 2 years after onset. After high-dose pulse methylprednisolone therapy, the illness had no mitigation. The above mentioned symptoms progressively worsened. At age 31, she subsequently developed ataxia, dysarthria, depression, and bowel and bladder urgency with occasional incontinence. And her hands became mild muscle atrophy one year later."}