Figure 1  Linkage of Chromosome 2 with ANA and Anti-Chromatin Abs in (129 × C57BL/6)F2.Apcs−/− Mice
These associations were not detected in (129 × C57BL/6)F2 animals. Centimorgan positions were deduced by interval mapping, anchoring marker locations to data from http://www.informatics.jax.org. Dotted lines and the dashed line indicate the threshold over which linkages were considered suggestive or significant, respectively, as defined in Materials and Methods.