Figure 7  The potential master regulator caspase 6 (pink rectangle) was identified for the cluster of both up-and down- regulated genes in naphthalene-treated mouse liver. The master regulator is shown at the top-most position of the schematic overview (pink rectangle), connecting molecules up to 10 steps upstream (green rectangles) starting from the identified transcription factors (blue rectangles). The diagram is a result of the workflow shown in Figure 5. See Supplementary Figure SF3 for high-resolution version.