Low grade NHL S.No. Types of NHL Description 1. Follicular lymphoma It is the most common type (25%) of B-cell low grade lymphoma in the UK. About 1 out of 5 lymphomas in the United Statesis follicular lymphoma. It mainly occurs in adults at site of lymph node and bone marrow over the age of 50. Over time about1 in 3 follicular lymphomas turns into a fast-growing diffuse B-cell lymphoma. 2. Mantle cell lymphoma Mantle cell lymphoma is a rare type of B-cell lymphoma. Mostly, It affects lymph node, bone marrow and often spleen overpeople in their 50s and 60s age. It is also a B-cell lymphoma. However, it is classified as low grade but it grows quickly andmay be treated more like high grade lymphomas. 3. Marginal zone B-cell lymphomas Marginal zone lymphomas are a group of slow growing B-cell lymphomas. They account 5% to 10% of lymphomas and tendto occur in people over the age of 60. The cells in these lymphomas look small under the microscope.There are 3 types of marginal zone lymphoma. Extra-nodal marginal zone B-cell lymphoma is also called mucosa associated lymphoid tissue lymphoma or MALT lymphoma-The most common site for MALT is the stomach due to infection of Helicobacter pylori. Nodal marginal zone lymphoma-It also called monocytoid B-cell lymphoma which occurs within the lymph nodes sometimes can found in bone marrow. It makes up about 2% and more common in women than men over the age of 60. Splenic marginal zone lymphoma-This is a rare type of lymphoma which associated with hepatitis-C virus infection. It starts in the spleen and can also be found in the bloodstream. This type makes up about 1% over the age 50. 4. Small lymphocytic lymphomaorCLL It is also called chronic lymphocytic leukemia (CLL). It makes up about 6% in the UK. In theory, Chronic lymphocyticleukemia is the term used for this condition if many of the abnormal cells are in the blood. Doctors call it small lymphocyticlymphoma when the disease particularly occurs in lymph nodes. 5. Lymphoplasmacytic lymphomas(including Wald Enstrom’smacroglobulinaemia) It accounts only 1 or 2% and specifically found in the bone marrow, lymph nodes, and spleen peoples over the age of 65. Itis slightly more common in men than women. People with Wald Enstrom’s macroglobulinaemia have a high level of a proteincalled immunoglobulin M (IgM) in their blood. The protein makes the blood thicker. 6. Skin lymphomas A rare type of NHL is mycosis fungoid. It affects the skin and is also called cutaneous T-cell lymphoma. 7. Hairy cell leukemia It is rare type B-cell lymphoma. It is typically found in the bone marrow and spleen and in the blood. Men are more likely toget HCL than women and the average age is around 50. 8. Primary central nervous system(CNS) lymphoma This lymphoma usually involves the brain (called primary brain lymphoma) but it may also be found in the spinal cord, inHIV infected people.