2.3. Data Extraction and Analysis We extracted the data including the author (nationality, affiliation, and component), sample size, characteristics of the participant (patients or the health, age, gender, race, handedness, emotional state, acupuncture experience, and accompanying symptoms), neuroimaging technology, acupuncture intervention (method of intervention, manipulation procedure, Deqi/needle sensation, and acupuncturist), and ethical review. The data analysis was conducted after data extraction.