4.2.6. Acupuncture Experience Some studies have reported the significant differences in cerebral response between the participant with acupuncture experience and the participant without acupuncture experience [198]. In our study, we found that participants in 44.04% of the studies were acupuncture naive. To ensure the consistency of the baseline of the participants and the comparability of consequence, the acupuncture experience of participants should be taken into consideration.