In this study, we found that there was a preponderance of nervous system disorders such as stroke among the diseases involved in acupuncture-neuroimaging studies. The result indicated that acupuncture stimulation promoted the action of neural rehabilitation and its mechanism is a focus of acupuncture study. Furthermore, we noticed that some studies were performed on functional disorders such as functional dyspepsia and irritable bowel syndrome [65, 101]. As we know, regulating functional disorder is the advantage of acupuncture, so functional disorder might be a new approach in future studies.