Owning to the complexity of the brain function and the diversity of acupuncture manipulations, the different or even reversed results occurring in similar acupuncture-neuroimaging studies become a common phenomenon. Seeking reasonable and practical methods is essential to improve the reproducibility and reliability of results in acupuncture-neuroimaging studies. Based on the open published literatures, this study analyzed the status of quality control in acupuncture-neuroimaging study for the first time and tried to provide some new ideas for future studies.