The subject clinical characteristics at screening are presented in Table 1. All subjects were young, healthy, normotensive, and nonobese. Subject weights, which were similar at baseline for each intervention, significantly declined following all interventions except control (hypocaloric ambulatory: 79.8 ± 3.6 vs. 78.4 ± 3.7 kg; hypocaloric bedrest: 78.7 ± 3.3 vs. 76.0 ± 3.3 kg; normocaloric bedrest: 78.1 ± 2.8 vs. 76.7 ± 2.8 kg; normocaloric ambulatory: 76.9 ± 3.2 vs. 76.7 ± 3.3 kg).
Table 1 Subject characteristics
Age (years) 24 ± 3
Height (cm) 182 ± 6
Weight (kg) 76 ± 7
BMI (kg/m2) 23 ± 9
Total cholesterol (mmol l−1) 4.2 ± 0.6
HDL (mmol l−1) 1.3 ± 0.3
LDL (mmol l−1) 2.5 ± 0.3
SBP (mmHg) 123 ± 6
DBP (mmHg) 78 ± 8
Values are mean ± SD
BMI body mass index, HDL high density lipoprotein, LDL low density lipoprotein, SBP systolic blood pressure, DBP diastolic blood pressure