Significant progress has been made in the area of POC diagnostic testing for the EBOV. The ability to rapidly and accurately determine the presence or absence of an infection in individuals who are at high risk of contracting the virus provides an especially appealing method in the setting of an active Ebola outbreak because infected individuals do not become infectious until the onset of clinical symptoms.[1686970] Consequently, the ability to identify those who are infected, but not yet acutely ill or actively infectious, provides two potentially unique benefits—early detection of those patients who require isolation, and the potential for instituting early antiviral therapy well before clinical symptoms appear. In a recently published report, the fingerstick ReEBOV rapid diagnostic test achieved 92% specificity and 100% sensitivity in both POC and reference laboratory testing in 28 reverse transcription polymerase chain reaction (RT-PCR) Ebola-positive patients and 77 RT-PCR Ebola-negative individuals; ReEBOV is the only rapid diagnostic test approved for use through an Emergency Use Authorization from the WHO and FDA.[7172]