N1, P1 and N2 latencies were not significantly different between HV and MAtot (p > 0.05) (Table 2).
Table 2 Latencies (in milliseconds) of VEPs in healthy volunteers (HV), the total group of migraine with aura patients (MAtot) and its subgroups with pure visual aura (MA) or visual aura associated with paraesthesia and/or dysphasia (MA+). Data are expressed as means ± SD.
Electrophysiological parameters (ms) HV (n = 30) MAtot (n = 47) MA (n = 27) MA+ (n = 20)
N1 (N75) 76.5 ± 6.4 75.7 ± 5.2 75.4 ± 5.8 75.9 ± 4.6
P1 (P100) 103.5 ± 5.9 103.1 ± 6.7 102.9 ± 5.7 103.4 ± 8.0
N2 (145) 144.2 ± 10.4 141.7 ± 11.9 140.6 ± 9.6 142.6 ± 11.4
Table 3 N1–P1 VEP component amplitude (μV) and habituation slope in healthy volunteers (HV), the total group of migraine with aura patients (MAtot) and its subgroups with pure visual aura (MA) or visual aura associated with paraesthesia and/or dysphasia (MA+). Data are expressed as means ± SD
N1-P1 HV (n = 30) MAtot (n = 47) MA (n = 27) MA+ (n = 20)
1st amplitude block (μV) 6.97 ± 2.90 7.28 ± 3.23 6.53 ± 3.36 8.27 ± 2.83
2nd amplitude block (μV) 7.15 ± 3.02 7.39 ± 3.23 6.43 ± 3.29 8.69 ± 2.70
3rd amplitude block (μV) 6.87 ± 2.79 7.40 ± 2.96 6.49 ± 2.83 8.64 ± 2.74
4th amplitude block (μV) 6.55 ± 2.74 7.16 ± 3.17 6.12 ± 3.07 8.57 ± 2.81
5th amplitude block (μV) 6.25 ± 2.57 7.34 ± 3.00 6.49 ± 2.97 8.49 ± 2.70
6th amplitude block (μV) 5.97 ± 2.63 7.42 ± 3.02 6.65 ± 3.09 8.45 ± 2.64
Slope −0.50 ± 0.36 +0.006 ± 0.40 +0.01 ± 0.30 +0.0049 ± 0.18
Table 4 P1-N2 VEP component amplitude (μV) and habituation slope in healthy volunteers (HV), the total group of migraine with aura patients (MAtot) and its subgroups with pure visual aura (MA) or visual aura associated with paraesthesia and/or dysphasia (MA+). Data are expressed as means ± SD
P1-N2 HV (n = 30) MAtot (n = 47) MA (n = 27) MA+ (n = 20)
1st amplitude block (μV) 6.59 ± 3.16 7.00 ± 3.07 6.12 ± 2.65 8.18 ± 3.26
2nd amplitude block (μV) 6.49 ± 3.03 6.87 ± 3.26 5.88 ± 2.55 8.20 ± 3.70
3rd amplitude block (μV) 6.49 ± 2.94 6.62 ± 3.10 5.67 ± 2.66 7.91 ± 3.25
4th amplitude block (μV) 5.99 ± 2.85 6.32 ± 2.88 5.37 ± 2.36 7.60 ± 3.08
5th amplitude block (μV) 6.26 ± 2.59 6.84 ± 2.93 6.01 ± 2.45 7.96 ± 3.19
6th amplitude block (μV) 5.61 ± 2.86 6.50 ± 2.78 5.78 ± 2.70 7.47 ± 2.64
Slope −0.35 ± 0.73 −0.09 ± 0.42 −0.06 ± 0.47 −0.13 ± 0.35