STX5  Parkinson's Disease Alzheimer's Disease  Trafficking defects and cytotoxicity in vitro in NRK and PC12 cell lines Regulates processing of APP in PC12, HeLa, COS-7, and NG108-15 cell lines and primary cultures of rat hippocampal neurons  Suga et al., 2005b; Thayanidhi et al., 2010; Rendón et al., 2013; Suga et al., 2015