As shown in Chen et al. (2014), we formulate the group analysis under a multivariate GLM or MVM platform that is expressed from a subject-wise perspective, βiT=xiTA+δiT, or through the variable-wise pivot, bj = Xaj + dj, or in the following concise form, (1) Bn×m=Xn×q   Aq×m+Dn×m.