(B) We assessed the enrichment of 69 breast-cancer-associated variants with various histone marks (H3K4me3 and H3K4me1) in the 118 tissues and cell types. Breast-cancer-associated SNPs were highly enriched (p = 2 × 10−3) in summit regions of H3K4me1 peaks in vHMECs (left panel), but not in other cells, H3K4me3 summit regions (p > 0.4), or H3K4me1 peak bodies. The stratified enrichment analysis indicated that the enrichment of H3K4me1 summit regions in vHMECs was independent of the H3K4me1 summit regions in the aggregated cell types and tissues. The H3K4me1 enrichment in vHMECs within summit regions was maintained when we stratified on summit regions from other breast tissues and cell types (p < 3.6 × 10−3; right panel).