In order to validate and visualize the phenotype annotations obtained for common disease, we constructed a CDN by computing the pairwise similarity of a total of 1,678 diseases (i.e., annotated MeSH entries) belonging to 13 DO categories such as “nervous system disease” (DOID: 863) or “respiratory system disease” (DOID: 1579) (Figure S2). Note that some diseases belong to multiple DO classes (Figure S3).