LBC Genotyping QC
DNA samples from each individual were genotyped with the Illumina Human610-Quad BeadChip. Individuals were excluded on the basis of unresolved gender discrepancy, relatedness, call rate (≤0.95), and evidence of non-European descent. SNPs were included in the analyses if they met the following conditions: call rate ≥ 0.98, minor allele frequency ≥ 0.01, and Hardy-Weinberg equilibrium test with p ≥ 0.001.