Power of EMIM when Using Simulated Case-Mother Duo Data
Powers of EMIM (for p value threshold 10−6) when using simulated case-mother duo data and assuming known parent of origin, parent of origin estimated with haplotype estimates from SHAPEIT2, or unknown (so, averaged over) parent of origin for any ambiguous duos. Tests of maternally inherited imprinting effects are shown on the top plot and maternally inherited imprinting effects conditional on child effects are shown on the lower plot.