PMC:4564992 / 50951-51365 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/4564992","sourcedb":"PMC","sourceid":"4564992","source_url":"https://www.ncbi.nlm.nih.gov/pmc/4564992","text":"Define r as the probability of a case-parent trio being phased, assuming independence with the genotypes. This is given by the proportion of trios that have been phased in the dataset. Referring to column 9 of Table 2 in Ainsworth et al,20 we then get∏i∈diseased,phasedP(gmi,gfi,gci|θ,disi=1,Ψi=1)P(Ψi=1|disi=1)=[rR2S2ImIpγ22μ1]n1′×…×[rR2S1ImIpγ12μ4]n8′×[rR1S1Ipγ11μ4]n9a′×[rR1S1Imγ11μ4]n9b′×[rS1μ4]n10′×[rμ6]n15′.","tracks":[]}