Proteins are vital macromolecules, at both cellular and systematic levels, but they rarely act alone. And protein-protein interactions (PPIs) are major bearers of the biological process. So, protein interaction network (PIN) could provide the basis of understanding cellular organization and processes. The GO [10] project is a collaborative effort to construct ontologies which facilitate biologically meaningful annotation of gene products. It provides a collection of well-defined biological terms, spanning biological processes, molecular functions, and cellular components. GO enrichment is a common statistical method used to identify shared associations between proteins and annotations to GO. Module-network and GO analysis may provide an efficient way to illustrate the molecular mechanism of QSYQ.