An epidermis was constructed of 6–7 layers of cells, including 1–2 keratinized layers. The intercellular spaces of squamous cells seemed wider than those of normal skin. Electron density of the squamous cells differed depending on the area in which they were distributed (Fig. 4D). The basement membrane was not clear, but the presence of many basal cells was confirmed (Fig. 4E). Oval or polygonal fibroblasts accounted for the majority in the dermis, and slim fibroblasts were few at this stage (Fig. 4E).