Kidney injury, oxidative, and inflammation marker levels in 36-week-old of human apoB Tg. SHR-cp/cp (n=9), non-Tg. SHR-cp/cp (n=8), human apoB Tg. SHR-+/+ (n=7), and non-Tg. SHR-+/+ rats (n=7). (A) Urinary KIM1 excretion, (B) Spp1 mRNA expression in the kidney cortex, (C) plasma thiobarbituric acid reactive substances (TBARS), and (D) plasma C-reactive protein (CRP) levels. The asterisks indicate a significant difference at *P<0.05 or **P<0.01 in comparison of human apoB Tg. SHR-cp/cp rats with their littermates.