Table 1. Metabolic parameters in human apoB Tg. SHR-cp/cp rats
ApoB Tg. cp/cp Non-Tg. cp/cp ApoB Tg. +/+ Non-Tg. +/+
n 9 8 7 7
Body weight (g) 911 ± 20.8 963 ± 8.6 520 ± 15.5** 541 ± 11.9**
Plasma insulin (ng/ml) 35 ± 5.9 23 ± 1.6 3 ± 0.2** 3 ± 0.3**
Plasma glucose (mg/dl) 202 ± 33.8 203 ± 26.9 129 ± 2.7 145 ± 2.5
Plasma TC (mg/dl) 1,513 ± 89.1 176 ± 9.2** 465 ± 10.1** 73 ± 1.8**
Plasma TG (mg/dl) 1,044 ± 61.4 313 ± 149.9** 361 ± 12.8** 82 ± 10.5**
Plasma human apoB (mg/dl) 1,147 ± 40.2 0 ± 0** 406 ± 11.6** 0 ± 0**
Plasma HDL-c (mg/dl) 18 ± 2.1 40 ± 2.3** 5 ± 0.3** 24 ± 1.0
Systolic blood pressure (mmHg) 139 ± 9.0 153 ± 2.0 150 ± 3.0 168 ± 4**
Data are shown as the mean ± SE. **P<0.01 compared with human apoB Tg.-cp/cp rats.