Over the past years, a number of epidemiological and clinical studies have reported an association between migraine and RLS [23–25, 27, 28]. In the present study, a similar association between migraine and RLS was found in the form of a higher RLS prevalence among migraineurs compared to non-headache controls. We further investigated the association between migraine and RLS in the different age groups and found that migraine and RLS showed a significant association in adults aged 19–29 and aged 40–49, but not in those aged 50–69 (Table 2). Among aged 30–39, a trend towards an association was observed.