Table 4 Clinical characteristics of migraine according to the presence of restless legs syndrome
Migraine with RLS, N =13 Migraine without RLS, N =130 P-value
Women, N (%) 10 (76.9) 97 (74.8) 0.867
Age, mean ± SD 39.8 ± 12.6 41.5 ± 12.5 0.640
Frequency per month, mean ± SD 5.8 ± 8.6 3.7 ± 6.0 0.251
Headache characteristics Unilateral, N (%) 9 (69.2) 72 (55.0) 0.323
Pulsating, N (%) 11 (84.6) 97 (74.8) 0.432
Moderate-to-severe intensity, N (%) 12 (92.3) 103 (78.6) 0.241
Aggravation by movement, N (%) 8 (61.5) 92 (70.2) 0.516
Associated symptoms Nausea, N (%) 11 (84.6) 114 (87.8) 0.742
Vomiting, N (%) 6 (46.2) 49 (38.2) 0.573
Photophobia, N (%) 8 (61.5) 76 (58.0) 0.806
Phonophobia, N (%) 10 (76.9) 91 (69.5) 0.575
Osmophobia, N (%) 7 (53.8) 61 (46.6) 0.616
Headache Impact test-6, mean ± SD 59.1 ± 9.4 53.7 ± 9.2 0.047
Visual analogue scale for pain intensity, mean ± SD 6.8 ± 2.2 6.1 ± 1.9 0.212
RLS restless legs syndrome, SD standard deviation