A significant increase in the prevalence of RLS was observed in both migraineurs with 1–10 attacks per month (12.5 %, OR = 2.0, 95 % CI = 1.3–3.2, p = 0.003) and migraineurs with >10 attacks per month (12.5 %, OR = 2.5, 95 % CI = 1.0–5.6, p = 0.038) relative to migraineurs with <1 attack per month (2.1 %) (Table 3).
Table 3 Prevalence and odds ratios of restless legs syndrome among migraineurs according to headache frequency
RLS N (%) OR (95 % CI)  P-value
Migraine <1 attack per month, N = 47 1 (2.1) Reference Reference
1–10 attacks per month, N = 80 10 (12.5) 2.0 (1.3–3.2) 0.003
>10 attacks per month, N = 16 2 (12.5) 2.5 (1.0–5.6) 0.038
CI confidence interval, OR odds ratio, RLS restless legs syndrome