Table 2 Prevalence and odds ratios of restless legs syndrome according to headache diagnosis Age group, No of participants/ No. of RLS Non-headache control, N = 1,422 Non-migraine headache, N = 1,130 Migraine, N = 143 No. of RLS (%) OR No. of RLS (%) OR (95 % CI) P-value No. of RLS (%) OR (95 % CI) P-value Aged 19–29, 542/12 4 (1.4) Reference 5 (2.2) 1.3 (0.4–5.0) 0.701 3 (12.0) 6.6 (1.2–36.8) 0.029 Aged 30–39, 604/34 6 (2.0) Reference 25 (9.3) 4.6 (1.8–12.0) 0.002 3 (7.1) 2.9 (0.6–13.4) 0.176 Aged 40–49, 611/20 3 (1.0) Reference 13 (4.7) 3.7 (1.0–13.5) 0.046 4 (10.3) 6.7 (1.5–33.5) 0.016 Aged 50–59, 529/35 17 (5.6) Reference 16 (7.8) 1.3 (0.6–2.7) 0.553 2 (9.1) 1.1 (0.2–5.6) 0.902 Aged 60–69, 409/41 21 (8.6) Reference 19 (12.8) 1.3 (0.6–2.5) 0.506 1 (6.7) 0.4 (0.1–4.0) 0.459 Total, 2695/142 51 (3.6) Reference 78 (6.9) 1.8 (1.3–2.7)a 0.002a 13 (9.1) 2.2 (1.1–4.3)a 0.018a CI confidence interval, OR odds ratio, RLS restless legs syndrome aAdjusted after sociodemographic variables and sleep quality