PMC:4504098 / 15431-16501 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/4504098","sourcedb":"PMC","sourceid":"4504098","source_url":"https://www.ncbi.nlm.nih.gov/pmc/4504098","text":"Conclusion\nWe found both molecular and serologic evidence of RESTV infection in multiple bat species in the Philippines. RESTV RNA was detected by quantitative PCR in oropharangeal swabs taken from Miniopterus schreibersii, with three samples yielding a product on hemi-nested PCR whose sequence had a single nucleotide difference from sequence of the pig isolate in Bulacan province. Further, uncorroborated qPCR detections may indicate RESTV nucleic acid in M. australis, C. brachyotis and Ch. plicata. In addition, we detected three seropositve A. jubatus using both Western blot and ELISA, suggesting that ebolavirus infection is taxonomically widespread in Philippine bats. However, given the evident low prevalence and low viral load of RESTV in bats, expanded surveillance in future studies is needed to elaborate our findings, and more broadly to elaborate the taxonomic and geographic occurrence of ebolaviruses in bats in the region. The recent detection of RESTV in pigs in China [18] highlights the need for the ecology of this virus to be better understood.","divisions":[{"label":"title","span":{"begin":0,"end":10}}],"tracks":[]}