Figure 5 Validation of the AM-Bound ECD Heterodimer Structure for the Intact AM1 Receptor Transiently Expressed in COS-7 Cells Concentration-response curves for each of the CLR (A) or RAMP2 (B) alanine substitution mutants tested with hAM in cAMP signaling assays. Data are represented as mean ± SEM. See also Table S4.