Orthologs and paralogs
Proteins encoded by orthologs or close paralogs of CACNA1H in vertebrate and invertebrate species were identified by a BLAST search. GenBank accessions included NP_066921.2 (Homo sapiens), O88427.3 (Mus musculus), XP_414830.4 (Gallus gallus), XP_002932520.2 (Silurana tropicalis), XP_002122425.1 (Ciona intestinalis) and NP_001024496.1 (Caenorhabditis elegans). Human α1 subunit paralogs were as previously described (Scholl et al., 2013).