(D) Tumor xenografts show significant growth inhibition of cells overexpressing WT ZNF750. Five representative tumors are shown: (from top to bottom) the SCR vector control, ZNF750 knockdown (ZNF750-si), wild-type ZNF750 (ZNF750-WT), and the p.Ser70∗ variant (ZNF750-S70X) (n = 6 per group). The graph at the bottom left shows tumor volumes. Immunohistochemical analyses of Ki-67 are also shown (in the images on the right [the scale bar represents 200 μm] and the graph at the bottom right). Data represent the mean ± SD. ∗∗p < 0.01, ∗p < 0.05.