Table 4  Results on Independent dataset PDB186 of different predictorsa
Methods  Acc(%)  MCC  Sn(%)  Sp(%)  AUC(%)
iDNA-Prot  67.20  0.344  67.70  66.70  83.30
DNA-Prot  61.80  0.240  69.90  53.80  79.60
DNAbinder  60.80  0.216  57.00  64.50  60.70
DNABIND  67.70  0.355  66.70  68.80  69.40
DNA-Threader  59.70  0.279  23.70  95.70  N/A
DBPPred  76.90  0.538  79.60  74.20  79.10
PSSM-DT  80.00  0.647  87.09  72.83  87.40
The six methods in the front of the table are six useful predicting methods for identification of DNA-binding proteins proposed in the past and were demonstrated to have good performance. The results of the six existing predicting methods and the SVM-PSSM-DT were achieved on the dataset PDB186 by their model trained on benchmark dataset.
aThe results of iDNA-Prot [16], DNA-Prot [74], DNAbinder[21], DNABIND [34], DNA-Threader [78] and DDPPred [75] were obtained from [75].