gene i ::gene j EGFR/ErbB :: PrYijR=1 PrYijP=1 Odds ratio Avg GEiP : Avg GEiR : Signaling pathway j Avg GEjP Avg GEjR AKT2::MAML2 §,¶ Notch signaling 0.5 0.03 16.67 87.71::76.59 96.84::78.6 MDM2::APC §,$ Wnt signaling 0.5 0.03 16.67 76.33::82.43 77.9::86.76 KIT::CDC73 § Wnt signaling 0.5 0.03 16.67 82.14::104.01 82.68::110.88 MDM2::CDC73 § Wnt signaling 0.5 0.03 16.67 76.33::104.01 77.9::110.88 KIT::GNAQ § GPCR signaling 0.5 0.03 16.67 82.14::130 82.68::139.33 MDM2::GNAQ §,$ GPCR signaling 0.5 0.03 16.67 76.33::130 77.9::139.33 KIT::TSHR § GPCR signaling 0.5 0.03 16.67 82.14::71.32 82.68::71.66 MDM2::TSHR § GPCR signaling 0.5 0.03 16.67 76.33::71.32 77.9::71.66 AKT2::APC ¶ Wnt signaling 0.5 0.03 16.67 87.71::82.43 96.84::86.76 AKT2::APC ¶ Hippo signaling 0.5 0.03 16.67 87.71::82.43 96.84::86.76 AKT2::CDH1 ¶ Hippo signaling 0.5 0.03 16.67 87.71::74.2 96.84::79.8 AKT2::GNAQ ¶ Gnrh signaling 0.5 0.03 16.67 87.71::130 96.84::139.33 AKT2::GNAQ ¶ Calcium signaling 0.5 0.03 16.67 87.71::130 96.84::139.33 AKT2::MDM2 ¶ p53 signaling 0.5 0.03 16.67 87.71::76.33 96.84::77.9 MDM2::AKT2 $ Regulation of toll-like 0.5 0.03 16.67 76.33::87.71 77.9::96.84 receptor signaling MDM2::AKT2 $ insulin signaling 0.5 0.03 16.67 76.33::87.71 77.9::96.84 MDM2::AKT2 $ RANKL/RANK signaling 0.5 0.03 16.67 76.33::87.71 77.9::96.84 MDM2::AKT2 $ AMPK signaling 0.5 0.03 16.67 76.33::87.71 77.9::96.84 MDM2::AKT2 $ MAPK signaling 0.5 0.03 16.67 76.33::87.71 77.9::96.84 MDM2::AKT2 $ Tweak signaling 0.5 0.03 16.67 76.33::87.71 77.9::96.84 MDM2::AKT2 $ Toll-like 0.5 0.03 16.67 76.33::87.71 77.9::96.84 receptor signaling MDM2::APC $ BDNF signaling 0.5 0.03 16.67 76.33::82.43 77.9::86.76 MDM2::APC $ Wnt signaling Netpath 0.5 0.03 16.67 76.33::82.43 77.9::86.76 MDM2::APC $ Wnt signaling 0.5 0.03 16.67 76.33::82.43 77.9::86.76 and Pluripotency MDM2::COL1A1 $ Nanoparticle-mediated 0.5 0.03 16.67 76.33::91.44 77.9::102.54 activation of receptor signaling MDM2::COL1A1 $ Osteoblast signaling 0.5 0.03 16.67 76.33::91.44 77.9::102.54 MDM2::GNAQ $ TSH signaling 0.5 0.03 16.67 76.33::130 77.9::139.33 MDM2::GNAQ $ Serotonin Receptor 2 0.5 0.03 16.67 76.33::130 77.9::139.33 and STAT3 signaling MDM2::GNAQ $ Serotonin Receptor 2 0.5 0.03 16.67 76.33::130 77.9::139.33 and ELK-SRF/GATA4 signaling MDM2::ITK $ T-Cell Receptor and 0.5 0.03 16.67 76.33::89.86 77.9::93.27 Co-stimulatory signaling MDM2::ITK $ Tcr signaling 0.5 0.03 16.67 76.33::89.86 77.9::93.27 MDM2::KIT $ Kit receptor signaling 0.5 0.03 16.67 76.33::82.14 77.9::82.68 MDM2::PAX5 $ ID signaling 0.5 0.03 16.67 76.33::68.91 77.9::71.02 MDM2::TSHR $ TSH signaling 0.5 0.03 16.67 76.33::71.32 77.9::71.66 AKT2::TP53 § Notch signaling 0.5 0.04 12.5 87.71::128.73 96.84::155.09 KIT::APC § Wnt signaling 0.5 0.04 12.5 82.14::82.43 82.68::86.76 KIT::MAML2 § Notch signaling 0.5 0.04 12.5 82.14::76.59 82.68::78.6 KIT::STK11 § IGF1R signaling 0.5 0.04 12.5 82.14::71.97 82.68::74.95 KIT::STK11 § insulin receptor signaling 0.5 0.04 12.5 82.14::71.97 82.68::74.95 KIT::TP53 § Notch signaling 0.5 0.04 12.5 82.14::128.73 82.68::155.09 MDM2::MAML2 §,$ Notch signaling 0.5 0.04 12.5 76.33::76.59 77.9::78.6 MDM2::STK11 § IGF1R signaling 0.5 0.04 12.5 76.33::71.97 77.9::74.95 MDM2::STK11 § insulin receptor signaling 0.5 0.04 12.5 76.33::71.97 77.9::74.95 MDM2::TP53 § Notch signaling 0.5 0.04 12.5 76.33::128.73 77.9::155.09 AKT2::GNAS ¶ Gnrh signaling 0.5 0.04 12.5 87.71::5465.46 96.84::6212.43 AKT2::GNAS ¶ Calcium signaling 0.5 0.04 12.5 87.71::5465.46 96.84::6212.43 AKT2::NF2 ¶ Hippo signaling 0.5 0.04 12.5 87.71::85.75 96.84::87.36 AKT2::TP53 ¶ P53 signaling 0.5 0.04 12.5 87.71::128.73 96.84::155.09 AKT2::TP53 ¶ Wnt signaling 0.5 0.04 12.5 87.71::128.73 96.84::155.09 CBL::CDH1 ¶ RAP1 signaling 0.5 0.04 12.5 194.46::74.2 208.45::79.8