Table 1  Primary findings from the analyses using signaling pathways from Reactome, KEGG and WikiPathway in breast cancer cell-line: SKBR3 (GSE38376)
Pathway  # of signaling  Pathway of  All  Distinct  All putative  Distinct  # of other
source  pathways  interest  Cross-talks  gene-pairs §  drug-resistant  gene-pairs ¶  signaling
of interest  cross-talks  pathways
REACTOME 23 EGFR 1,083 841 104 97 13
KEGG 35 ErbB 2,179 1,050 188 99 26
WikiPathway 63 ErbB 3,084 876 299 96 51
¶Number of distinct gene-pairs involved in all EGFR/ErbB cross-talks with all other signaling pathways; §Number of distinct gene-pairs commonly involved in all EGFR/ErbB cross-talks and drug resistance.