Third, we found no support for previous hypotheses suggesting multiple migration events. On the contrary, our results provide multiple lines of evidence that support a single migration wave moving into Northwest Greenland and southward along the west coast and then finally reaching the east coast by passing the south tip of Greenland. It should be noted that we cannot determine from currently available data whether there have been multiple migrations into North Greenland (Qaanaaq) from Canada. The current population in Qaanaaq originated from a migration of central Canadian Inuit in the 17th century, and in 1864 a little group of Inuit from Baffin Island arrived in the Thule district.43 This should, however, not change the conclusion of our analyses given that the current population there would be similar to the previous one. However, to be extra careful, we also performed the same analyses by using Upernavik villages instead of Qaanaaq and obtained similar results. What we can conclude is that the data are not compatible with several migrations along the coast of West Greenland or East Greenland, because both Qaanaaq and Upernavik villages form an outgroup to East and West Greenland.