Finally, in addition to having a historically small population size, Inuit populations have traditionally lived in small groups, where the probability of mating with a comparatively closely related partner is increased. To investigate to what extent this has affected the population genetically, we estimated inbreeding coefficients for all the individuals and stratified the results according to location (Figure S10). If no admixture correction was performed, the inbreeding coefficients in some locations were estimated to be extremely high with an average value above 0.13. However, after correction for admixture, the average inbreeding coefficients were similar among locations in Greenland; they ranged from F = 0.008 to F = 0.014 and were comparable to coefficients estimated for the Danes (F = 0.007). The individuals with the lowest amount of inbreeding were Greenlanders living in Denmark.