The Full Data Set
To make this data set, we combined (1) genetic data from all genotyped participants of the IHIT cohort and the general population health survey (B99) from 15 locations in Greenland (Figure 1), (2) genetic data from all genotyped participants of the cohort of Greenlanders living in Denmark, and (3) genetic data from 50 Danish individuals from the Inter99 cohort. After merging the data sets, we removed all individuals who appeared in more than one cohort so that each individual was represented only once. We also removed all individuals with more than 2% missing genotypes among the SNPs with a minor allele frequency (MAF) above 1% and all individuals with misspecified or missing gender information. This left us with 4,127 Greenlandic individuals living in Greenland, 547 Greenlandic individuals living in Denmark, and 50 Danish individuals for a total of 4,724 individuals. From this data set we removed all SNPs with a MAF below 5% and/or more than 1% missingness, which left us with data from 92,362 SNPs, of which 92,151 were autosomal. The nonautosomal SNPs were only included in analyses where this is specifically stated.