Rigoli et al., 2010 Family-based association methods Italian (320) Overweight (103), obese (30) and non-obese controls (187) 1475A>G SNP (3′-UTR of exon 3) Higher allele frequencies in overweight (0.07) and obese (0.08) children compared to non-obese unrelated controls (children and/or adults) (0.02); preferential transmission of 1475G allele from heterozygous parents to overweight and obese offspring Early-onset obesity N/A N/A