Vasseur et al., 2007 Sequence variability screen and haplotype analysis French Caucasian (840) General population sample 5′ SNPs: −3608T>C, −1702C>T, −175A>G (promoter region) NSD in allele frequency between subjects with different BMI; strong linkage disequilibrium between the SNPs, haplotypic effect attributed to −3608T>C N/A ↓ Plasma LDL-cholesterol level and LDL/HDL ratio; potential protection against atherogenesis Potential association with lipid metabolism and atherogenicity